Mei Hu Selected Research

leukotriene D4 receptor (cysteinyl leukotriene receptor)

4/2017	Hippocampal CysLT1R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice.
2/2017	Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo.
1/2017	CysLT1R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice.
12/2016	Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice.
5/2016	Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice.
9/2014	Montelukast rescues primary neurons against Aβ1-42-induced toxicity through inhibiting CysLT1R-mediated NF-κB signaling.
4/2014	Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice.

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Mei Hu Research Topics

Disease

19	Neoplasms (Cancer) 05/2022 - 10/2002
17	Neuroinflammatory Diseases 01/2020 - 02/2013
15	Cognitive Dysfunction 01/2022 - 08/2012
13	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2013
9	Infections 06/2022 - 12/2003
8	Memory Disorders (Memory Loss) 02/2017 - 02/2013
5	Neoplasm Metastasis (Metastasis) 05/2022 - 01/2018
5	Inflammation (Inflammations) 01/2022 - 04/2015
4	Shock 01/2017 - 04/2014
4	Asthma (Bronchial Asthma) 04/2015 - 04/2014
3	Closed Head Injuries 01/2022 - 03/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2015
3	Fibrosis (Cirrhosis) 10/2021 - 12/2014
3	Hypertension (High Blood Pressure) 01/2020 - 01/2017
3	Hyperlipidemias (Hyperlipidemia) 01/2018 - 08/2012
3	Insulin Resistance 11/2017 - 08/2012
3	Hyperglycemia 01/2017 - 08/2012
2	Obesity 01/2022 - 01/2017
2	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2021 - 01/2020
2	Hypoxia (Hypoxemia) 01/2021 - 05/2017
2	Sarcoma (Soft Tissue Sarcoma) 01/2018 - 10/2002
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2017 - 01/2017
2	Necrosis 10/2016 - 06/2009
2	Chronic Traumatic Encephalopathy 03/2015 - 03/2015
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2014 - 04/2013
2	Brain Ischemia (Cerebral Ischemia) 12/2007 - 04/2007
2	Hepatitis E 03/2005 - 12/2003
1	Triple Negative Breast Neoplasms 05/2022
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022
1	Heart Failure 01/2022
1	Heart Valve Diseases (Valvular Heart Disease) 01/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022
1	Crohn Disease (Crohn's Disease) 01/2022
1	Sepsis (Septicemia) 01/2022

Drug/Important Bio-Agent (IBA)

11	Amyloid (Amyloid Fibrils)IBA 08/2021 - 02/2013
8	Peptides (Polypeptides)IBA 01/2022 - 02/2013
7	Pharmaceutical PreparationsIBA 05/2022 - 10/2016
7	CytokinesIBA 01/2022 - 04/2014
7	LipopolysaccharidesIBA 01/2020 - 02/2014
7	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 04/2017 - 04/2014
5	Caspase 3 (Caspase-3)IBA 08/2021 - 04/2014
5	Streptozocin (Streptozotocin)FDA Link 01/2017 - 08/2012
4	Neuroprotective AgentsIBA 01/2022 - 10/2018
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2014
3	Paclitaxel (Taxol)FDA LinkGeneric 05/2022 - 01/2020
3	Monoacylglycerol LipasesIBA 01/2022 - 03/2015
3	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2022 - 03/2015
3	EnzymesIBA 01/2022 - 03/2015
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022 - 08/2012
3	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2020
3	MicroRNAs (MicroRNA)IBA 04/2021 - 02/2014
3	Immunoglobulin M (IgM)IBA 01/2021 - 12/2003
3	Simvastatin (Zocor)FDA LinkGeneric 01/2020 - 01/2017
3	MicellesIBA 01/2018 - 11/2012
3	ProdrugsIBA 01/2018 - 07/2009
3	pranlukastIBA 01/2017 - 02/2013
3	montelukast (Singulair)FDA Link 12/2016 - 04/2014
2	LigandsIBA 01/2022 - 01/2022
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	EndocannabinoidsIBA 01/2022 - 03/2015
2	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 11/2021
2	Angiotensin IIIBA 10/2021 - 01/2020
2	AntibodiesIBA 01/2021 - 03/2005
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 11/2019
2	Immune Checkpoint InhibitorsIBA 01/2021 - 12/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2016
2	AntigensIBA 12/2020 - 02/2019
2	VaccinesIBA 12/2020 - 08/2012
2	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2020 - 01/2018
2	zileuton (Zyflo)FDA Link 01/2020 - 01/2018
2	N(1)-methylnicotinamideIBA 12/2019 - 01/2019
2	6alpha-ethyl-23(S)-methylcholic acidIBA 10/2019 - 10/2018
2	PolymersIBA 01/2018 - 06/2012
2	Nonesterified Fatty Acids (NEFA)IBA 11/2017 - 01/2016
2	oridoninIBA 05/2017 - 01/2017
2	LipidsIBA 01/2017 - 02/2013
2	Blood Glucose (Blood Sugar)IBA 01/2016 - 04/2013
2	Pioglitazone (Actos)FDA Link 04/2013 - 08/2012
2	Leukotriene D4IBA 02/2013 - 02/2013
2	Coloring Agents (Dyes)IBA 06/2009 - 04/2007
2	Immunoglobulin G (IgG)IBA 03/2005 - 12/2003
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 06/2022
1	IsoenzymesIBA 06/2022
1	Interleukin-2 (IL2)IBA 05/2022
1	polyethylene glycol polyethyleneimine nanogelIBA 05/2022
1	AntioxidantsIBA 01/2022
1	Cyclic PeptidesIBA 01/2022
1	AcidsIBA 01/2022
1	CreatinineIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	Therapeutic UsesIBA 01/2022
1	Gallium-68IBA 01/2022
1	Protein Tyrosine PhosphatasesIBA 01/2022
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2022
1	BoronIBA 01/2022

Therapy/Procedure

7	Therapeutics 01/2022 - 02/2013
5	Immunotherapy 05/2022 - 01/2020
4	Drug Therapy (Chemotherapy) 01/2021 - 12/2014
1	Boron Neutron Capture Therapy 01/2022